Retail integration
Walgreens EDI integration for suppliers
A guide for suppliers connecting with Walgreens, covering distribution center and direct store delivery flows, the documents involved and ERP integration.
Overview
Understanding Walgreens integration
Who this is for: Consumer health, beauty, pharmacy and general merchandise suppliers shipping to Walgreens distribution centers or delivering directly to stores.
Walgreens exchanges orders, shipment information and invoices with suppliers through EDI and manages its supplier relationships through a supplier portal. Third-party sources describe the purchase order, advance ship notice and invoice as the core documents, with functional acknowledgments confirming receipt, and note that invoices are matched against the order and the shipment.
Walgreens supports more than one delivery model. Suppliers shipping to distribution centers follow one flow, while direct store delivery suppliers deliver to individual stores and invoice each delivery. Walgreens' own direct store delivery invoice guide states that each invoice should represent a single delivery to a store with line item detail, and that Walgreens only recognizes invoices from vendors who have passed testing. It also asks vendors to notify Walgreens and re-test after changes to their EDI software, mapping or versions.
Suppliers should confirm their specific requirements, documents and testing steps through Walgreens' supplier portal.
Workflows
Typical Walgreens business workflows
Distribution center replenishment
- 1Receive 850 purchase order
- 2Ship to the distribution center
- 3Send 856 ship notice
- 4Send 810 invoice
Direct store delivery
- 1Receive store order
- 2Deliver to the store
- 3Send one invoice per delivery
- 4Reconcile payment
Documents and APIs
Common Walgreens transactions
Documents commonly exchanged with Walgreens, based on the public sources listed below. Exact requirements depend on your program, so always confirm against Walgreens's current implementation guide.
| Document | Name | Direction | Purpose |
|---|---|---|---|
| 850 | Purchase Order | From Walgreens | Walgreens orders products. |
| 856 | Advance Ship Notice | To Walgreens | Describes shipments to distribution centers. |
| 810 | Invoice | To Walgreens | Requests payment. For direct store delivery each invoice covers one store delivery. |
| 997 | Functional Acknowledgment | Both directions | Confirms documents were received. |
Connectivity
How companies connect
VAN AS2 or FTP
Third-party sources list VAN, AS2 and FTP connections for Walgreens EDI.
Supplier portal
Walgreens manages supplier onboarding and offers a web-based option for suppliers that are not EDI capable.
Challenges
Common integration challenges
Two delivery models
Distribution center and direct store delivery flows have different document rules.
Three-way matching
Invoices must reconcile with the purchase order and the shipment.
Re-testing after changes
Changes to EDI software or maps can require re-testing with Walgreens.
How ECOM helps
How ECOM can support your Walgreens integration
EDI Integration
Integrate Walgreens documents for both distribution center and store delivery models.
ProductPRISM-SCV
Monitor ship notices and invoice matches across Walgreens orders.
ServiceMapping and Translation
Maintain Walgreens maps and manage re-testing when changes are needed.
ERP integration options
ECOM integrates Walgreens documents with ERP and route accounting or warehouse systems, so distribution center and store delivery invoices are generated correctly from each delivery.
Visibility and exception management
PRISM-SCV, ECOM's supply chain visibility product, is designed to follow each Walgreens document from receipt to response and flag late or missing documents and mismatches, so your team can resolve exceptions before they affect the relationship.
Explore PRISM-SCVWalgreens integration FAQs
Which EDI documents does Walgreens use?
Third-party sources consistently cite the 850 purchase order, 856 ship notice, 810 invoice and 997 functional acknowledgment. Confirm through Walgreens' supplier portal.
How does direct store delivery invoicing work with Walgreens?
Walgreens' direct store delivery invoice guide says each invoice should represent a single delivery to a store and include line item detail.
Do we need to re-test after changing EDI software?
Walgreens' guide asks vendors to notify Walgreens and re-test after changes to EDI software, mapping or versions.
Is ECOM an approved Walgreens provider?
This page is an integration guide and does not indicate an approval or partnership with Walgreens. ECOM builds integrations to Walgreens' published requirements.
Sources and accuracy
This guide summarizes publicly available information as of October 2026. Walgreens sets its own requirements and can change them at any time; your Walgreens implementation guide, supplier portal or account contact is the authoritative source for your program.
- Walgreens DSD 810 invoice guide (hosted by SPS Commerce) Third-party source
- Logicbroker, Walgreens EDI specifications Third-party source
Walgreens is a trademark of its owner. Its mention does not imply endorsement of, or a partnership with, ECOM Specialist.
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Request Walgreens integration assistance
Tell us about your Walgreens program, documents and ERP. We will outline the connection, mapping and testing plan.